Heart Failure
Conditions
Interventions
PiCCO-directed treatment group:treatment directed by conventional monitor combined with PiCCO monitor
Conventional treatment group:treatment directed by conventional monitor
Sponsors
Shanghai Chest Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients with heart failure of different causes, especially those who need fluid-management or those who are accompanied with other complicated diseases. For example, heart failure accompanied with unstable haemodynamics, cardiorenal syndrome, or cardiogenic liver damage, which is caused by ischemic cardiomyopathy, other kinds of cardiomyopathy, or myocarditis; 2. Patients with heart failure who need hemodynamic monitoring in order to make differential diagnosis; 3. Sever cases who need to be monitored, in order to guide application of vasoactive agents and fluid-management, such as those who are with acute cardiac failure, ARDS, pulmonary arterial hypertension, and hypertensive emergencies; 4. More than 18 years old; 5. Agree to sign a informed consent form; 6. Agree to comply with the research programme.
Exclusion criteria
Exclusion criteria: 1. Patients who are not appropriate for intravascular catheter placement, such as those with peripheral vascular diseases, artery transplantation, puncture site infection, blood coagulation disorders, allergy to heparin; 2. anatomical or physiological derangements likely to render PiCCO-derived measurements grossly inaccurate, such as arrhythmia (e.g. atrial fibrillation), mechanical circulatory assist devices (e.g. IABP, extracorporeal circulation), aortic valve pathology, sever valvular regurgitation, intracardial shunt (e.g. ASD, VSD), sever pneumothorax, lobectomy surgery, massive pulmonary embolism; 3. Pregnant or lactating women; 4. Psychopath; 5. Patients who are taking other experimental drugs; 6. Non-cooperative patients and patients who did not sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality rate;rehospitalization rate;time from hospital discharge to rehospitalization;length of hospital stay;hospitalization expense;6-MWD;QOL;BNP;LVEF;size of all chambers of the heart;adverse event rate; | — |
Countries
China
Contacts
Public ContactMin Zhang
Shanghai Chest Hospital
Outcome results
None listed