Women with recurrent miscarriage, recurrent implantation failure, or with infertility undergoing IVF treatment
Conditions
Interventions
Case series :This project is an observational one. During the study, the procedure would be the same as per current practice,except saving two inner catheters instead of one.
Sponsors
Department of Obstetrics and Gunaecology, The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Aged 20-40 years; Women with recurrent miscarriage, recurrent implantation failure, or with infertility undergoing IVF treatment.;Inclusion criteria: Aged 20-40 years; Women with recurrent miscarriage, recurrent implantation failure, or with infertility undergoing IVF treatment.
Exclusion criteria
Exclusion criteria: Uncorrected uterine anomalies, such as septate or bicornuate uterus, fibroids (submucous/intramural); Intrauterine adhesions; Adenomyosis; Systematic disease that may cause subfertility, such as diabetes or systemic lupus erythematosus.;Exclusion criteria: Uncorrected uterine anomalies, such as septate or bicornuate uterus, fibroids (submucous/intramural); Intrauterine adhesions; Adenomyosis; Systematic disease that may cause subfertility, such as diabetes or systemic lupus erythematosus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endometrial response to infection as measured by plasma cell count, uNK cell count and Toll like receptor expression in archived endometrial tissue specimen from several groups of women with reproductive failure.;;endometrial response to infection as measured by plasma cell count, uNK cell count and Toll like receptor expression in archived endometrial tissue specimen from several groups of women with reproductive failure.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbiome in uterine fluid at time of ET will be examined, as well as correlate findings with the various clinical outcomes of ET.;;Microbiome in uterine fluid at time of ET will be examined, as well as correlate findings with the various clinical outcomes of ET.; | — |
Countries
China
Contacts
Public ContactProf Li Tin Chiu;Prof Li Tin Chiu ;
Chinese University of Hong Kong;Chinese University of Hong Kong
Outcome results
None listed