heart failure
Conditions
Interventions
Control Group:5%GS 250mL +KCL 0.5g+ RI 2U/iv.drip st
Shenmai Injection Group:5% GS 250mL +Shenmai Injection 40mL+ RI 2U/iv.drip st
Sponsors
The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 79 Years
Inclusion criteria
Inclusion criteria: (1) Age 40 to 79; (2) To fit the diagnostic criteria of chronic heart failure; (3) NYHA Class II to IV; (4) Corresponded with the TCM syndrome differentiation criteria of both qi- yin deficiency.
Exclusion criteria
Exclusion criteria: 1. Age below 40 or above 79; 2. BNP less than 200pg/mL; 3. Acute heart failure; 4. Those diagnosed with one of the following diseases: (1) Acute myocardial infarction within 4 weeks; (2) Pulmonary heart disease; (3) Severe valvular heart disease; (4) Hypertrophic obstructive cardiomyopathy; (5) Congenital heart disease; (6) Acute pulmonary embolism; (7) Pre-excitation syndrome; (8) Stroke within 6 months; (9) Acute myocarditis; 5. Those who suffered from severe hepatic or renal impairment; 6. Those with severe endocrine diseases such as hyperthyroidism; 7. Those with severe anemia, hemoglobin (HB) less than 9g/dl; 8. Those with mental disorder; 9. Those women who are pregnant, planning for pregnancy or breastfeeding; 10. Those who participated in other studies within the past 2 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BNP;TCM clinical symptoms scores;Metabonomics; | — |
Countries
China
Contacts
Public ContactJingyuan Mao
Outcome results
None listed