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A randomized, single blind clinical study of human umbilical cord mesenchymal stem cells compare sodium hyaluronate to treatment of early osteoarthritis of the knee

A randomized, single blind clinical study of human umbilical cord mesenchymal stem cells compare sodium hyaluronate to treatment of early osteoarthritis of the knee

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17014226
Enrollment
Unknown
Registered
2017-12-30
Start date
2018-03-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

B:human Umbilical Cord -Mesenchymal Stem Cells group

Sponsors

Tianjin First Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 65 Years

Inclusion criteria

Inclusion criteria: 1. Knee osteoarthritis not more than 6 months of conservative treatment; 2. The VAS score was less than 6; 3. The knee joint activity decreased; 4. The K-L score was lower than grade 3; 5. The patient aged under 65 years; 6. Patients with primary osteoarthritis of the knee.

Exclusion criteria

Exclusion criteria: 1. Autoimmune arthropathy; 2. Unstable or damaged ligaments; 3. There was infection, surgery and radioactivity for the knee joint within 6 weeks; 4. The immunosuppressant was made in 6 weeks; 5. Glucocorticoids or sodium hyaluronate were injected within 3 months; 6. Pregnant or lactating women; 7. Abnormal coagulation function; 8. Infection in the skin of the injection area. 9. The investigator cognizanced the patients unsuitable in the study.

Design outcomes

Primary

MeasureTime frame
X-ray;Nuclear Magnetic Resonance Imaging;VAS score;WOmAC score;

Countries

China

Contacts

Public ContactWenxue Jiang

Tianjin First Central Hospital

jiangwenxue1920@163.com+86 13752002876

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026