Postoperative cognitive dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male and female aged 60-90 years old; 2. Patients graded I to III level of American Society of anesthesiologists (American Socitey of Anesthesiology, ASA) grading standard; 3. BMI 18 to 28Kg/m2; 4. Patients with hip fracture surgery; 5. Patients agreed to participate in the test, and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with liver function or renal function obviously abnormal; 2. Patients with high risk of blood; 3. The electrocardiogram were significantly abnormal; 4. Hypertension patients with unsatisfactory control of blood pressur; 5. Diabetic patients with unsatisfactory blood glucose control (Fasting plasma glucose=11mmol/L); 6. Patients with skin infection of anesthesia puncture site; 7. Patients with peripheral nerve lesion or surgical lateral limb nerve injury; 8. Patients participated in other clinical trials within 30 days; 9. Patients who researchers think them should not participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative cognitive dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative nausea and vomiting;Postoperative Pulmonary infection;deep venous thrombosis;pain intensity after 48 hours of surgery;The first time to get out of bed after surgery;Length of stay;Hospitalization expense;patient satisfaction;Doctor satisfaction;The amount of morphine remediation after 48 hours of surgery;The death rate of the patient after six months of surgery;The incidence of chronic pain after six months of surgery; | — |
Countries
China
Contacts
Shanghai Tongji Hospital