Off-pump coronary artery bypass grafting patients
Conditions
Interventions
BIS group:Propofol, sufentanil and rocuronium were administered using closed-loop titration guided by BIS
CON group:Propofol, sufentanil and rocuronium were manually administered
Sponsors
The Affiliated Yantai Yuhuangding Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients undergoing first-time elective CABG with good or only slightly reduced left ventricular function (ejection fraction>40%; left ventricular end diastolic pressure <15mmHg) and aged <70 year.
Exclusion criteria
Exclusion criteria: Patients requiring extra corporeal circulation either electively or during the course of the operation; renal insufficiency (creatinine >1.5 mg/dL), hepatic impairment (alanine aminotransferase or aspartate aminotransferase >40 U/mL), misuse of alcohol or drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arterial plasma levels of ACTH;Arterial plasma levels of cortisol;The course of anesthesia, surgery; actual consumption of anesthetics and additional drugs;Intraoperative recall; | — |
Countries
China
Contacts
Public ContactMa Jiahai
The Affiliated Yantai Yuhuangding Hospital of Qingdao University
Outcome results
None listed