Chronic kidney disease
Conditions
Interventions
2:western medicine + traditional Chinese medicine granules
Sponsors
Renji Hospital affiliated to Shanghai jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. CKD2-4 stage (eGFR: 15 ~ 90 ml / min / 1.73m2); 2. 24 hours proteinuria = 3.0g; 3. Aged 18-70 years old; 4. In line with one of traditional Chinese medicine symptoms spleen and kidney Qi dificiency; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Does not meet the diagnosis of chronic kidney disease, non-CKD2-4 stage; 2. 24h proteinuria quantitative> 3.0g who; 3. Combine life-threatening complications, such as serious infections, new malignant tumors, severe water and electrolyte imbalance, severe heart, brain, liver, hematopoietic system and gastrointestinal diseases and other important organs or disorders; 4. allergic to the drug; 5. Mental illness patients; 6. Pregnant or lactating women; 7. Receiving other clinical trials; 8. using immunosuppressive therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression of chronic kidney disease: serum creatinine doubled from baseline;Patient enter the ESRD stage;The time to reach the endpoint; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proteinuria increased by 50% from baseline;New onset of cardiovascular events requiring hospitalization;New onset of infection requiring hospitalization; | — |
Countries
China
Contacts
Public ContactZhaohui Ni
Renji Hospital affiliated to Shanghai jiaotong University School of Medicine
Outcome results
None listed