primary liver cancer
Conditions
Interventions
experimental group:arsenic trioxide
control group:common theray
Sponsors
Union Hospital, Tongji Medical College, Huazhong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18~70 years old; 2. The diagnosis of primary hepatocellular carcinoma (HCC); 3. Complete resection of HCC; 4. Child - Pugh A, B (less than 7) level (only two indicators of albumin and bilirubin Child - Pugh rating in one of 2); 5. The KPS score is more than 50; 6. The tumor was exposed; 7. A combined resection of a satellite or a focal point; 8. Vascular or bile duct embolus under the microscope; 9. Expentance of survival period is more than 6 months; 10. Normal heart and kidney function.
Exclusion criteria
Exclusion criteria: 1. Pregnancy and lactation period; 2. Complication of other tumors or active liver cancer; 3. Extensive metastasis has occurred in the whole body; 4. The liver function severer than the Child-Pugh C grade; 5. The blood platelet count was less than 100 x 10^9, which could not be corrected. 6. Uncontrolled medical or acute infection; 7. With disease of the nervous system, brain or meningeal metastasis; 8. Other clinical trials of similar drugs have been involved in the last 2 months; 9. Allergy to arsenic and related compounds; 10. Other systemic antitumor drugs were accepted within 3 months; 11. Chemotherapy can not be completed because of severe side effects; 12. The patient is unable to understand the purpose of the study or disagree with the requirements of the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;one year survival; | — |
Primary
| Measure | Time frame |
|---|---|
| Progression free survival;three year survival;three year survival;safety and tolerance; | — |
Countries
China
Contacts
Public ContactJun Xiong
Union Hospital, Tongji Medical College, Huazhong University
Outcome results
None listed