Cancer-related fatigue, CRF
Conditions
Interventions
Experimental group:Routine treatment + Shenmai injection (100ml ivd,qd, d1-5)
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. with histologically or cytologically confirmed NSCLC; 2. clinical stage IIIB, IIIC or IV; 3. Clinical confirmed cancer related fatigue; 4. TCM syndrome is deficiency of qi; 5. scores of fatigue =4 within 24h; 6. Aged from 18 to 75-years-old; 7. Eastern Cooperative Oncology Group (ECOG) performance status score 1 to 2; 8. Adequate organ function; 9. Accepted chemotherapy (AP, TP, DP or GP regimen); 10. Hemoglobin is higher than 90g/L; 11. Normal thinking and ability to read and write in Chinese; 12. Good compliance and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Diagnosed with central nervous system metastasis that has not yet been treated with surgery and/or radiation; 2. Active double cancer; 3. A history of mental disease (anxiety or severe depression) or cognitive dysfunction; 4. Any evidence of active tuberculosis and other serious infectious diseases; 5. Received previous radiotherapy or targeted drug therapy within one month; 6. Received APO and oral or intravenous proprietary Chinese medicine reinforcing Qi; 7. Severe hypersensitivity to shenmai injection and its components; 8. Currently pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| assessment of CRF; | — |
Secondary
| Measure | Time frame |
|---|---|
| assessment of anxiety and depression;Sleep quality assessment;life quality evaluation; | — |
Countries
China
Contacts
Public ContactYu-Shu Zhou
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed