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Clinical observation of percutaneous vagus nerve stimulation in the treatment of post herpes zoster neuralgia and the study of the mechanism of central nervous inflammation regulation

Clinical observation of percutaneous vagus nerve stimulation in the treatment of post herpes zoster neuralgia and the study of the mechanism of inflammation regulation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013589
Enrollment
Unknown
Registered
2017-11-29
Start date
2017-11-29
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post herpetic neuropathic pain

Interventions

Contral:The stimulation site is the upper ear canoe (the middle of the outer ear)
Vagus stimulation:The stimulation site is underneath the external auditory canal

Sponsors

Shandong Provincial Hospital affiliated to the Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with herpes zoster in the course of more than 3 months

Exclusion criteria

Exclusion criteria: 1. aged 80 years old; 2. excludes patients with substance dependence; 3. severe depressive patients or patients with severe suicidal tendencies; 4. patients with severe physical disease; 5. cannot adhere to the therapist for long distance or other reasons; 6. Herpes in the head and the perineum.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale;—

Secondary

MeasureTime frame
CD71;nAChRa 7, ChAT;IL-6, TNF-a, IL-1ß;—

Countries

China

Contacts

Public ContactShengtao Wang

Shandong Provincial Hospital affiliated to the Shandong University

wshengt@126.com+86 18853111889

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026