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A randomized controlled trial: The efficacy and safety of The Dingji Fumai Decoction combined with metoprolol in the treatment of ventricular premature contractions

A randomized controlled trial: The efficacy and safety of The Dingji Fumai Decoction combined with metoprolol in the treatment of ventricular premature contractions

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013548
Enrollment
Unknown
Registered
2017-11-26
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ventricular arrhythmia

Interventions

Group 1:Dingji Fumai Decoction combined with metoprolol
Group 2:Metoprolol

Sponsors

Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Diagnostic criteria: TCM syndrome diagnostic criteria and symptom scores of Chinese medicine standards: refer to "Chinese new drug clinical research guidelines 2010 trial version".Western diagnostic criteria: Ventricular premature contraction: QRS wave occurred in advance with no or related P wave. QRS wave is broad deformity and its time limit is usually more than 0.12s, the direction of ST segment and T wave is opposite to the main wave of QRS wave, and the matching period is constant with a complete compensatory interval. Ventricular tachycardia: 3 or more premature ventricular contractions occur continuously, the ventricular rate is usually 100-250 bpm, heart rhythm regular or slightly irregular, the onset suddenly start, there are atrioventricular separation, ventricular seizure or ventricular fusion wave.

Exclusion criteria

Exclusion criteria: Non-ventricular tachyarrhythmia patients. Patients with a high degree of anxiety and depression (SAS =70 or SDS=72) and psychiatric patients. Patients who are susceptible to infection and hemorrhage, and allergies. Patients with severe complications or primary disease complicated by cardiovascular, liver, kidney, digestive, endocrine, hematopoietic system, etc. Pregnant, lactating women and women who have fertility requirements for nearly six months. Patients who is participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Holter;

Secondary

MeasureTime frame
TCM syndrome score;Blood routine test;Liver function test;Kidney function test;

Countries

China

Contacts

Public ContactLiao Huiling

Southwest Medical University

157776358@qq.com+86 13909081952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026