actinic keratoses
Conditions
Interventions
Daylight-PDT Group:Daylight-PDT
Sponsors
Shanghai Skin Disease Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Clinical diagnosed with AK (OLSEN classification grade I, II, III), aged > 18 years; (2) All patients are unfit and reluctant to undergo surgery for any reasons, and volunteered to participate in the study and signed informed consent. Patents are willing to pay for the treatment, and agreed to take a picture of the skin lesions.
Exclusion criteria
Exclusion criteria: (1) Those who had ALA-PDT and any other studies that affect this study within 12 weeks ; (2) There are other facial diseases that may affect the efficacy evaluation, such as other photodermatosis; (3) Take phototoxic or photosensitizer within 8 weeks; (4) clinical and / or pathological prove that the tumor has invaded other organs or tissues; (5) Serious immunocompromised persons; (6) scar constitution; (7) Patients are known to have skin photosensitivity, porphyria, or allergies to ALA, light or lidocaine; (8) Persons are suffering from severe internal diseases, mental and mental illness, infectious diseases or pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete clearance rate of AK lesions at month 1 after PDT; | — |
Secondary
| Measure | Time frame |
|---|---|
| New AKs during following up;Recurrence time of AK;Pain and pruritus score after and during treatment;Other side effects rate; | — |
Countries
China
Contacts
Public ContactXiuli Wang
Shanghai Skin Disease Hospital
Outcome results
None listed