Onychomycosis
Conditions
Interventions
combination group:2940-nm Er: YAG fractional laser combined with Amorolfine hydrochloride
single group:Amorolfine hydrochloride
Sponsors
Sun Yat-sen Memorial Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) there are no gender limits for patients aged between 18 and 65 years; (2) patients with onychomycosis confirmed by clinical manifestations and fungal microscopy, the fungal direct microscopy was positive and the OSI score was greater than 1; (3) consent and consent to sign informed consent; (4) women of childbearing age agree to take effective contraceptive measures during the trial period.
Exclusion criteria
Exclusion criteria: (1) the affected areas may affect the evaluation of the skin diseases (such as methylitis, pterygium, etc.); (2) known history of allergy to romero liniment; (3) patients with severe immunosuppression or within 3 months of systemic use of glucocorticoid and immunosuppressive agents; (4) patients with severe heart, liver and kidney disease (ALT, AST > normal value of 2 times, Cr > normal value limit 1.2 times); (5) patients with severe neurological, mental illness and poor control of diabetes; (6) the application of antifungal drugs or antifungal drugs within 3 months prior to the treatment of antifungal drugs in the previous 2 weeks; (7) women who are pregnant, breast-feeding, planning to conceive or use improper contraception; (8) having a history of drug abuse; (9) have participated in other drug clinical trials within 3 months before treatment; (10) for other reasons, the researcher does not consider it suitable for participating in this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mycological clear rate; | — |
Countries
China
Contacts
Public ContactZhang Jing
Outcome results
None listed