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Influence of different drugs on incidene of adverse reactions introduced by hemabate during cesarean section: A prospective randomized controlled study

Influence of different drugs on incidene of adverse reactions introduced by hemabate during cesarean section: A prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013500
Enrollment
Unknown
Registered
2017-11-23
Start date
2017-12-30
Completion date
Unknown
Last updated
2018-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section

Interventions

Midazolam:intravenously midazolam (0.02mg kg-1) 20mL
dexmedetomidine:intravenously dexmedetomidine (1ug kg-1) 20mL

Sponsors

Department of Anesthesiology, The Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. women aged 20-40 years; 2. need to be treated with hemabate intraoperatively; 3. patients who were arranged to undergo scheduled cesarean section under epidural anesthesia.

Exclusion criteria

Exclusion criteria: 1. long-term opioid pain relieving utilization or NSAIDs, sedative utilization, mental illnesses; 2. preoperative heart rate (HR) lower than 50bpm with atrial-ventricular conduction abnormalities or rhythm irregularities, neuromuscular and endocrine sicknesses; 3. hypersensitive reactions to a2-adrenergic receptor agonists; 4. There are contraindications to epidural anesthesia,such as coagulation disfunction,local anesthetic allergy etc; 5. with severe heart,kindey,liver or respiratory diseases.

Design outcomes

Primary

MeasureTime frame
Nausea;vomiting;

Secondary

MeasureTime frame
headache;headache;chest congestion;facial flushing;satisfaction score;Ramsay score;BIS score;1 min, 5 min, 10 min and 30 min vital signs after hemabate injection;

Countries

China

Contacts

Public ContactBailong Hu

The Affiliated Hospital of Guizhou Medical University

375896605@qq.com+86 15185184309

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026