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Autologous mitochondria transfer improves oocyte quality

The effect of autologous mitochondria transfer from bone marraw mesenchymal stem cells on oocyte quality: a randomized control study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013499
Enrollment
Unknown
Registered
2017-11-23
Start date
2017-12-01
Completion date
Unknown
Last updated
2017-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Experimental group:mitochondria transfer
Control:ICSI fertilization

Sponsors

Sixth affiliated hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20-45years; 2. A normal BMI (18<BMI<30); 3. A normal uterine cavity with normal endometrial thickness; 4. Repeated IVF failure due to poor oocyte quality or advanced age.

Exclusion criteria

Exclusion criteria: 1. Severe Adenomyosis; 2. Abnormal uterine cavity, such as intrauterine adhesions; 3. PCOS patients; 4. History of allergic to ovulation induction medicines; 5. Attending other clinical trials in the same period.

Design outcomes

Primary

MeasureTime frame
High quality embryo rate;2PN rate;cleavage rate;transferrable embryo rate;—

Secondary

MeasureTime frame
hCG positive rate;clinical pregnancy rate;live birth rate;—

Countries

China

Contacts

Public ContactLiang Xiao-yan

Sixth affiliated hospital of Sun Yat-sen University

lxyzy@263.net+86 13500015058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026