refractory diarrhea-predominant irritable bowel syndrome
Conditions
Interventions
A:FMT
B:probiotics
Sponsors
The Affiliated Third Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) male or female, aged 16 to 60; 2) in accordance with irritable bowel syndrome diagnostic criteria of the Roman ?, patients are diagnosised Diarrhea-Predominant Irritable Bowel Syndrome; 3) the patients were diagnosedDiarrhea-Predominant Irritable Bowel Syndrome more than 3 months,and they have used conventional drug treatment,but no obvious obvious effect or break out repeatedly; 4) no other serious disease, mental disorders, and have ability of normal communication; 5) signed informed consent, agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1) complicated with other serious heart, liver, kidney, respiratory, digestive, blood, endocrine system disease; 2) with double infection of the gut, such as CDI, enterohemorrhagic escherichia coli, salmonella, hayes bacteria, campylobacter, plague, and cytomegalovirus; 3) abnormal liver function or any of the following history of liver disease: 2 times higher than normal amount of AST and ALT limit, liver cirrhosis, hepatic encephalopathy history, history of esophageal varices or portal vein shunt; 4) abnormal kidey function or the following kidney disease: serum creatinine:> 1.5 times normal limit; The history of dialysis; history of nephrotic syndrome; 5) concurrence various acute infection, tumor, and serious arrhythmia, mental system disorders, drug or alcohol addiction; 6) Unable to complete the site visit, or the various factors influencing the compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal pain score;number of diarrhoea and BSFS; | — |
Countries
China
Contacts
Public ContactChen Dongfong
The Affiliated Third Hospital of Army Medical University
Outcome results
None listed