hepatocellular carcinoma
Conditions
Interventions
A:TAE+MWA
B:TACE+MWA
Sponsors
Guangdong General Hospital (Guangdong Academy of Medical Sciences)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Aged 18~70-year-old patients with hepatocellular carcinoma, the expected survival period at least 3 months; (2) the number of tumors is less than 3; (3) The tumor diameter of large hepatocellular carcinoma greater than 5 cm and less than 15 cm; (4) no cancer tied in portal vein or inferior vena cava; (5) can be completely embolized,although the dynamic-venous fistula or arterial-portal fistula is exist (6) Child-Pugh grade A or B grade ,Child score = 7; ECOG physical status score <2; (7) no bleeding tendency, normal coagulation function or coagulation dysfunction being corrected; (8) white blood cell count = 3.0×10^9/L; (9) hemoglobin = 8.5g/dl; (10) platelet count = 75×10^9/L; (11) International Normalized Ratio (INR) = 1.7 or prothrombin time (PT) does not exceed 3 seconds than the normal control upper limit; (12) serum creatinine was less than 1.5 times the normal upper limit; (13) Patients and / or their families agree to join the clinical trials and sign informed consent.;Inclusion criteria: (1) Aged 18~70-year-old patients with hepatocellular carcinoma, the expected survival period at least 3 months; (2) the number of tumors is less than 3; (3) The tumor diameter of large hepatocellular carcinoma greater than 5 cm and less than 15 cm; (4) no cancer tied in portal vein or inferior vena cava; (5) can be completely embolized,although the dynamic-venous fistula or arterial-portal fistula is exist (6) Child-Pugh grade A or B grade ,Child score = 7; ECOG physical status score <2; (7) no bleeding tendency, normal coagulation function or coagulation dysfunction being corrected; (8) white blood cell count = 3.0×10^9/L; (9) hemoglobin = 8.5g/dl; (10) platelet count = 75×10^9/L; (11) International Normalized Ratio (INR) = 1.7 or prothrombin time (PT) does not exceed 3 seconds than the normal control upper limit; (12) serum creatinine was less than 1.5 times the normal upper limit; (13) Patients and / or their families agree to join the clinical trials and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) diffuse type of liver cancer; (2) liver function classification for Child-Pugh C level, can not improve by liver protection therapy; (3) large number of intractable ascites; (4) combined with active infections, especially inflammation of bile duct; (5) serious disease of heart, lung, kidney, and brain or other vital organs;;Exclusion criteria: (1) diffuse type of liver cancer; (2) liver function classification for Child-Pugh C level, can not improve by liver protection therapy; (3) large number of intractable ascites; (4) combined with active infections, especially inflammation of bile duct; (5) serious disease of heart, lung, kidney, and brain or other vital organs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CT image;;CT image; | — |
Countries
China
Contacts
Public ContactRongde Xu;Rongde Xu ;
Guangdong General Hospital (Guangdong Academy of Medical Sciences);Guangdong General Hospital (Guangdong Academy of Medical Sciences)
Outcome results
None listed