AIDS
Conditions
Interventions
routine antiretroviral therapy group :antiretroviral therapy
routine antiretroviral therapy+ HANK immunotherapy group:antiretroviral therapy+HANK immunotherapy
Sponsors
Tianjin Secondary people's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. continuous antiviral treatment > 24 months; 2. viral load (HIV-RNA) of plasma was lower than 20 CP/ml when screening ; 3. the number of CD 4+ T cells in the peripheral blood was less than 200 cells/ul during antiviral treatment; 4. Before meeting the criterion, the patients should have no tumors and no active opportunistic infection (AIDS III and IV symptoms) at least 4 weeks; 5. The patients should be informed consent and comply with the requirement by this study; 6. The patients should not participate in other studies within 6 months.
Exclusion criteria
Exclusion criteria: 1. with other serious disease such as urinary, circulation, respiration, nerve, spirit, digestive, endocrine, immune system disease or tumor; 2. pregnancy or lactation, including taking no effective contraceptive measures when possible pregnant; 3. allergic to blood products or other test products; 4. drug addiction in one year before the test; 5. low complianace; unable or unwilling to provide informed consent or failure to comply with the research requirements; 6. Other conditions that interfere with clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the number of CD4+ T cells; | — |
Secondary
| Measure | Time frame |
|---|---|
| CD4/CD8+T cell ratio;cytokine concentration;HIV-RNA plasma viral load; | — |
Countries
China
Contacts
Public ContactPing Ma
Outcome results
None listed