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Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 35-60 years male and female; Understand trial procedure and content and sign informed consent voluntarily; 2. No active skin disease on the face; 3. No facial filler such as hyaluronic acid or laser/light treatment; 4. No oral steroids,collagen powder/liquid,or topical hyaluronic acid used in the last 3 monthes; 5. No skin whitening products in the last 2 weeks.
Exclusion criteria
Exclusion criteria: 1. She is pregnant or in breast-feeding period; 2. To be allergic to trial medicine or its ingredient. No facial filler such as hyaluronic acid or laser/light treatment; 3. She/he had severe cardiovascular, cerebrovascular, renal, hepatic or hematopoietic disease; 4. She/he is taking part in the other clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin pores;skin texture;skin winkle;UV spots;black brown spots;Erythema;skin hydration;skin transepidermal water loss;skin elasticity;skin melanin index;skin erythema index; | — |
Countries
China
Contacts
Beijing Friendship Hospital affiliated to Capital Medical University