Skip to content

The effect of nonfluent aphasia after ischemic cerebral infarction complicated with cognitive impairment: a comparative study of repetitive transcranial magnetic stimulation and diffusion tensor tractography

The effect of nonfluent aphasia after ischemic cerebral infarction complicated with cognitive impairment: a comparative study of repetitive transcranial magnetic stimulation and diffusion tensor tractography

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013288
Enrollment
Unknown
Registered
2017-11-08
Start date
2017-11-01
Completion date
Unknown
Last updated
2017-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke aphasia

Interventions

double stimulation group:bilateral repetitive transcranial magnetic stimulation
single stimulation group:unilateral repetitive transcranial magnetic stimulation

Sponsors

Zhujiang Hospital of Southern Medical University, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients aged between 18-75years old three months to twleve months after ischemic stroke; 2. The stroke was first episode,?according to the guidelines for Chinese cerebrovascular disease prevention and treatment, ischemic stroke was supported ,?and the lesions in the left hemisphere (CT or MRI confirmed); 3. Dextromanuality,non-fluent aphasia, complicated with cognitive impairment; 4. There was no significant improvement in language ability and cognitive impairment after routine medical treatment; 5. No other neurological history (such as epilepsy, Parkinson's disease, brain injury, etc.), no stent implantation history, good cooperation to the treatment; 6. clear consciousness, grade school culture degree or above; 7. signed the informed.

Exclusion criteria

Exclusion criteria: 1. patients with cerebral hemorrhage or hemorrhagic cerebral infarction; 2. Nuclear magnetic resonance or transcranial magnetic stimulation contraindications; 3. Verbal communication failure (severe cognitive impairment, severe hearing loss, etc); 4. the critical condition of the patient,unstable life signs.

Design outcomes

Primary

MeasureTime frame
Aphasia Battery of Chinese;Non-Language-Based Cognitive Assessment;FA value;Apparent diffusion coefficient;Nerve fiber number;

Secondary

MeasureTime frame
Montreal Congnitive Assessment;SPECT;

Countries

China

Contacts

Public ContactSheng Tan

Zhujiang Hospital of Southern Medical University

tansheng18@126.com+86 13802548208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026