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Effect of preoperative budesonide inhalation on arterial blood oxygenation and intrapulmonary shunt in patients received one-lung ventilation

Effect of preoperative budesonide inhalation on arterial blood oxygenation and intrapulmonary shunt in patients received one-lung ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013284
Enrollment
Unknown
Registered
2017-11-07
Start date
2016-07-01
Completion date
Unknown
Last updated
2017-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

2:Preoperative budesonide inhalation
1:Preoperative inhalation of 0.9% N.S

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Aged 45 yr to 65 years, height 155-176cm, weight 45-75kg, body mass index(BMI)18-27kg/m2, ASA Physical Status Classifications I to II, left-lateral position during one-lung ventilaion, normal cardiac and pulmonary function, and no cardiac, hepatic, renal and endocrine disease.

Exclusion criteria

Exclusion criteria: FEV1/FVC<70%, asthma,chronic obstructive pulmonary disease, acute lung infection, past history of thoracic surgery. preoperative glucocorticoid medication, preoperative chemotherapy, SpO2 kept below 90% for more than 15 minutes during operation, blood transfusion during operation, OLV less than an hour, occurrence of severe complications like allergic shock.

Design outcomes

Primary

MeasureTime frame
Arterial blood oxygenation(PaO2);Intrapulmonary shunt(Qs/Qt);—

Countries

China

Contacts

Public ContactWenhua Chen
whc6202@163.com+86 13365910975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026