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Efficacy and Safety of Intravitreal Conbercept, Ranibizumab and Triamcinolone on 23-Gauge Vitrectomy for patients with Proliferative Diabetic Retinopathy

Efficacy and Safety of Intravitreal Conbercept, Ranibizumab and Triamcinolone on 23-Gauge Vitrectomy for patients with Proliferative Diabetic Retinopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013215
Enrollment
Unknown
Registered
2017-11-02
Start date
2015-01-02
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proliferative Diabetic Retinopathy

Interventions

Three groups:Intravitreal injection of anti-VEGF drugs

Sponsors

The First Hospital of Qiqihar
Lead Sponsor

Eligibility

Sex/Gender
All
Age
29 Years to 78 Years

Inclusion criteria

Inclusion criteria: Between Jan 2015 and Dec 2015, 53 patients of varying degrees of PDR in the First Hospital of Qiqihar were collected (60 eyes). There were 33 (55%) male and 27 (45%) female. The age was between 29-78 years old, with the average age of 58.83 (+/-3.62). Mean duration of DM was 26.57±5.82 years. All patients had a history of DM;Inclusion criteria: Between Jan 2015 and Dec 2015, 53 patients of varying degrees of PDR in the First Hospital of Qiqihar were collected (60 eyes). There were 33 (55%) male and 27 (45%) female. The age was between 29-78 years old, with the average age of 58.83 (+/-3.62). Mean duration of DM was 26.57±5.82 years. All patients had a history of DM;Inclusion criteria: Between Jan 2015 and Dec 2015, 53 patients of varying degrees of PDR in the First Hospital of Qiqihar were collected (60 eyes). There were 33 (55%) male and 27 (45%) female. The age was between 29-78 years old, with the average age of 58.83 (+/-3.62). Mean duration of DM was 26.57±5.82 years. All patients had a history of DM;Inclusion criteria: Between Jan 2015 and Dec 2015, 53 patients of varying degrees of PDR in the First Hospital of Qiqihar were collected (60 eyes). There were 33 (55%) male and 27 (45%) female. The age was between 29-78 years old, with the average age of 58.83 (+/-3.62). Mean duration of DM was 26.57±5.82 years. All patients had a history of DM;Inclusion criteria: Between Jan 2015 and Dec 2015, 53 patients of varying degrees of PDR in the First Hospital of Qiqihar were collected (60 eyes). There were 33 (55%) male and 27 (45%) female. The age was between 29-78 years old, with the average age of 58.83 (+/-3.62). Mean duration of DM was 26.57±5.82 years. All patients had a history of DM

Exclusion criteria

Exclusion criteria: Exclusion criteria included those who received prior intravitreal injection, underwent vitreous or retinal surgeries, and glaucoma. Patients with abnormal blood coagulation indexes and other diseases of surgical contraindication were also excluded.;Exclusion criteria: Exclusion criteria included those who received prior intravitreal injection, underwent vitreous or retinal surgeries, and glaucoma. Patients with abnormal blood coagulation indexes and other diseases of surgical contraindication were also excluded.;Exclusion criteria: Exclusion criteria included those who received prior intravitreal injection, underwent vitreous or retinal surgeries, and glaucoma. Patients with abnormal blood coagulation indexes and other diseases of surgical contraindication were also excluded.;Exclusion criteria: Exclusion criteria included those who received prior intravitreal injection, underwent vitreous or retinal surgeries, and glaucoma. Patients with abnormal blood coagulation indexes and other diseases of surgical contraindication were also excluded.;Exclusion criteria: Exclusion criteria included those who received prior intravitreal injection, underwent vitreous or retinal surgeries, and glaucoma. Patients with abnormal blood coagulation indexes and other diseases of surgical contraindication were also excluded.

Design outcomes

Primary

MeasureTime frame
BCVA;

Secondary

MeasureTime frame
Time of operation;The incidence of iatrogenic retinal breaks;Use of the Intraocular coagulation;Use of Silicone filling;Vitreous clear time;The incidence of intraoperative and postoperative bleeding;intraocular pressure;Systemic complications and the incidence of systemic disease;

Countries

China

Contacts

Public ContactWeikuan Gu, Hong Chen, Jinglin Cui;Weikuan Gu, Hong Chen, Jinglin Cui;Weikuan Gu, Hong Chen, Jinglin Cui;Weikuan Gu, Hong Chen, Jinglin Cui;Weikuan Gu, Hong Chen, Jinglin Cui ;;;;

;;;;

wgu@uthsc.edu;wgu@uthsc.edu;wgu@uthsc.edu;wgu@uthsc.edu;wgu@uthsc.edu+1-9013552782,13504611060;+1-9013552782,13504611060;+1-9013552782,13504611060;+1-9013552782,13504611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026