non small cell lung cancer
Conditions
Interventions
Two groups:different whole brain dose of Intensity Modulated Radiation Therapy With Simultaneous Integrated Boost (SIB-IMRT)
Sponsors
Taizhou Hospital of Zhejiang Province
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. a histopathologically or cytologically proven non-small cell lung cancer(NSCLC) and an axial gadolinium-enhanced T1 sequence magnetic resonance scan(MRI) confirmed brain metastases(BMs) and symptomatic brain metastases. 2. have an estimated survival of at least 4 weeks; 3. Karnofsky Performance Status Scale (KPS) of 60-100; 4. Patients laboratory values had to meet these restrictions: hemoglobin>100g/L, platelets>70*10^9/L, white blood cells>4*10^9/L; 5. sign the consent form.;Inclusion criteria: 1. a histopathologically or cytologically proven non-small cell lung cancer(NSCLC) and an axial gadolinium-enhanced T1 sequence magnetic resonance scan(MRI) confirmed brain metastases(BMs) and symptomatic brain metastases. 2. have an estimated survival of at least 4 weeks; 3. Karnofsky Performance Status Scale (KPS) of 60-100; 4. Patients laboratory values had to meet these restrictions: hemoglobin>100g/L, platelets>70*10^9/L, white blood cells>4*10^9/L; 5. sign the consent form.;Inclusion criteria: 1. a histopathologically or cytologically proven non-small cell lung cancer(NSCLC) and an axial gadolinium-enhanced T1 sequence magnetic resonance scan(MRI) confirmed brain metastases(BMs) and symptomatic brain metastases. 2. have an estimated survival of at least 4 weeks; 3. Karnofsky Performance Status Scale (KPS) of 60-100; 4. Patients laboratory values had to meet these restrictions: hemoglobin>100g/L, platelets>70*10^9/L, white blood cells>4*10^9/L; 5. sign the consent form.;Inclusion criteria: 1. a histopathologically or cytologically proven non-small cell lung cancer(NSCLC) and an axial gadolinium-enhanced T1 sequence magnetic resonance scan(MRI) confirmed brain metastases(BMs) and symptomatic brain metastases. 2. have an estimated survival of at least 4 weeks; 3. Karnofsky Performance Status Scale (KPS) of 60-100; 4. Patients laboratory values had to meet these restrictions: hemoglobin>100g/L, platelets>70*10^9/L, white blood cells>4*10^9/L; 5. sign the consent form.;Inclusion criteria: 1. a histopathologically or cytologically proven non-small cell lung cancer(NSCLC) and an axial gadolinium-enhanced T1 sequence magnetic resonance scan(MRI) confirmed brain metastases(BMs) and symptomatic brain metastases. 2. have an estimated survival of at least 4 weeks; 3. Karnofsky Performance Status Scale (KPS) of 60-100; 4. Patients laboratory values had to meet these restrictions: hemoglobin>100g/L, platelets>70*10^9/L, white blood cells>4*10^9/L; 5. sign the consent form.
Exclusion criteria
Exclusion criteria: 1. patients had major medical illnesses or psychiatric impairments which will prevent completion of the protocol therapy; 2. patients who had received previous brain irradiation; 3. Patients laboratory values could not match the inclusion criteria; 4. could not be regularly followed; 5. with leptomeningeal involvement.;Exclusion criteria: 1. patients had major medical illnesses or psychiatric impairments which will prevent completion of the protocol therapy; 2. patients who had received previous brain irradiation; 3. Patients laboratory values could not match the inclusion criteria; 4. could not be regularly followed; 5. with leptomeningeal involvement.;Exclusion criteria: 1. patients had major medical illnesses or psychiatric impairments which will prevent completion of the protocol therapy; 2. patients who had received previous brain irradiation; 3. Patients laboratory values could not match the inclusion criteria; 4. could not be regularly followed; 5. with leptomeningeal involvement.;Exclusion criteria: 1. patients had major medical illnesses or psychiatric impairments which will prevent completion of the protocol therapy; 2. patients who had received previous brain irradiation; 3. Patients laboratory values could not match the inclusion criteria; 4. could not be regularly followed; 5. with leptomeningeal involvement.;Exclusion criteria: 1. patients had major medical illnesses or psychiatric impairments which will prevent completion of the protocol therapy; 2. patients who had received previous brain irradiation; 3. Patients laboratory values could not match the inclusion criteria; 4. could not be regularly followed; 5. with leptomeningeal involvement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| magnetic resonance image; | — |
Countries
China
Contacts
Public ContactHaihua Yang;Haihua Yang;Haihua Yang;Haihua Yang;Haihua Yang ;;;;
Taizhou Hospital of Zhejiang Province;Taizhou Hospital of Zhejiang Province;Taizhou Hospital of Zhejiang Province;Taizhou Hospital of Zhejiang Province;Taizhou Hospital of Zhejiang Province
Outcome results
None listed