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Study on the mechanism of the related complications of tracheal intubation with liquorice spray and its clinical effect

Study on the mechanism of the related complications of tracheal intubation with liquorice spray and its clinical effect

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17013168
Enrollment
Unknown
Registered
2017-10-30
Start date
2017-12-01
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic cholecystectomy

Interventions

Placebo group, :The drug was sprayed into the mouth before the induction tracheal intubation, and the throat was fully infiltrated
lidocaine group,:The drug was sprayed into the mouth before the induction tracheal intubation, and the throat was fully infiltrated
liquorice spray group:The drug was sprayed into the mouth before the induction tracheal intubation, and the throat was fully infiltrated

Sponsors

Gansu Provincial Hospital of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: During Dec. 2017 to Dec. 2019 accept laparoscopic surgery anesthesia (60 endotracheal intubation time 10 minutes) patients meet ASA (American Society of Anesthesiologists, and the American Society of Anesthesiologists) I ~ II, not alcohol drunker, and tobacco hobby; without cold fever and respiratory symptoms, good for intubation (reference for classification and grade I ~ II, mouth is good for open, can expose uvula, soft palate), aged 18 to 60 years old male and female, body mass index (BMI) < 28.;Inclusion criteria: During Dec. 2017 to Dec. 2019 accept laparoscopic surgery anesthesia (60 endotracheal intubation time 10 minutes) patients meet ASA (American Society of Anesthesiologists, and the American Society of Anesthesiologists) I ~ II, not alcohol drunker, and tobacco hobby; without cold fever and respiratory symptoms, good for intubation (reference for classification and grade I ~ II, mouth is good for open, can expose uvula, soft palate), aged 18 to 60 years old male and female, body mass index (BMI) < 28.;Inclusion criteria: During Dec. 2017 to Dec. 2019 accept laparoscopic surgery anesthesia (60 endotracheal intubation time 10 minutes) patients meet ASA (American Society of Anesthesiologists, and the American Society of Anesthesiologists) I ~ II, not alcohol drunker, and tobacco hobby; without cold fever and respiratory symptoms, good for intubation (reference for classification and grade I ~ II, mouth is good for open, can expose uvula, soft palate), aged 18 to 60 years old male and female, body mass index (BMI) < 28.;Inclusion criteria: During Dec. 2017 to Dec. 2019 accept laparoscopic surgery anesthesia (60 endotracheal intubation time 10 minutes) patients meet ASA (American Society of Anesthesiologists, and the American Society of Anesthesiologists) I ~ II, not alcohol drunker, and tobacco hobby; without cold fever and respiratory symptoms, good for intubation (reference for classification and grade I ~ II, mouth is good for open, can expose uvula, soft palate), aged 18 to 60 years old male and female, body mass index (BMI) < 28.;Inclusion criteria: During Dec. 2017 to Dec. 2019 accept laparoscopic surgery anesthesia (60 endotracheal intubation time 10 minutes) patients meet ASA (American Society of Anesthesiologists, and the American Society of Anesthesiologists) I ~ II, not alcohol drunker, and tobacco hobby; without cold fever and respiratory symptoms, good for intubation (reference for classification and grade I ~ II, mouth is good for open, can expose uvula, soft palate), aged 18 to 60 years old male and female, body mass index (BMI) < 28.

Exclusion criteria

Exclusion criteria: Severe liver and kidney function; The coagulant function is unusual; Heart function level and level of the above; Patients with severe hypertension (SBP >160mmhg or/and DBP>110mmHg); Preoperative cold fever, infection and other inflammatory manifestations of the patient; Clinical performers such as throat discomfort, cough, expectorant phlegm, etc. Patients used analgesics and steroid drugs before the operation; Other conduit (such as a stomach tube) in the mouth or nasal cavity; The duration of the operation will longer than 5 hrs or less than 1 hour; After anaesthesia induction, the tracheal intubation was found to be difficult and the laryngoscope was exposed to the laryngeal hemorrhage in the intubation. Airbag inflating pressure control at 25cmH 20, mechanical ventilation has air leakage;Exclusion criteria: Severe liver and kidney function; The coagulant function is unusual; Heart function level and level of the above; Patients with severe hypertension (SBP >160mmhg or/and DBP>110mmHg); Preoperative cold fever, infection and other inflammatory manifestations of the patient; Clinical performers such as throat discomfort, cough, expectorant phlegm, etc. Patients used analgesics and steroid drugs before the operation; Other conduit (such as a stomach tube) in the mouth or nasal cavity; The duration of the operation will longer than 5 hrs or less than 1 hour; After anaesthesia induction, the tracheal intubation was found to be difficult and the laryngoscope was exposed to the laryngeal hemorrhage in the intubation. Airbag inflating pressure control at 25cmH 20, mechanical ventilation has air leakage;Exclusion criteria: Severe liver and kidney function; The coagulant function is unusual; Heart function level and level of the above; Patients with severe hypertension (SBP >160mmhg or/and DBP>110mmHg); Preoperative cold fever, infection and other inflammatory manifestations of the patient; Clinical performers such as throat discomfort, cough, expectorant phlegm, etc. Patients used analgesics and steroid drugs before the operation; Other conduit (such as a stomach tube) in the mouth or nasal cavity; The duration of the operation will longer than 5 hrs or less than 1 hour; After anaesthesia induction, the tracheal intubation was found to be difficult and the laryngoscope was exposed to the laryngeal hemorrhage in the intubation. Airbag inflating pressure control at 25cmH 20, mechanical ventilation has air leakage;Exclusion criteria: Severe liver and kidney function; The coagulant function is unusual; Heart function level and level of the above; Patients with severe hypertension (SBP >160mmhg or/and DBP>110mmHg); Preoperative cold fever, infection and other inflammatory manifestations of the patient; Clinical performers such as throat discomfort, cough, expectorant phlegm, etc. Patients used analgesics and steroid drugs before the operation; Other conduit (such as a stomach tube) in the mouth or nasal cavity; The duration of the operation will longer than 5 hrs or less than 1 hour; After anaesthesia induction, the tracheal intubation was found to be difficult and the laryngoscope was exposed to the laryngeal hemorrhage in the intubation. Airbag inflating pressure control at 25cmH 20, mechanical ventilation has air leakage;Exclusion criteria: Severe liver and kidney function; The coagulant function is unusual; Heart function level and level of the above; Patients with severe hypertension (SBP >160mmhg or/and DBP>110mmHg); Preoperative cold fever, infection and other inflammatory manifestations of the patient; Clinical performers such as throat discomfort, cough, expectorant phlegm, etc. Patients used analgesics and steroid drugs before the operation; Other conduit (such as a stomach tube) in the mouth or nasal cavity; The duration of the operation will longer than 5 hrs or less than 1 hour; After anaesthesia induction, the tracheal intubation was found to be difficult and the laryngoscope was exposed to the laryngeal hemorrhage in the intubation. Airbag inflating pressure control at 25cmH 20, mechanical ventilation has air leakage

Design outcomes

Primary

MeasureTime frame
SBP;SpO2;DAP;HR;MAP;bucking;dysphoria;pharyngalgia;trachyphonia;

Countries

China

Contacts

Public ContactLingyun Zhang;Lingyun Zhang;Lingyun Zhang;Lingyun Zhang;Lingyun Zhang ;;;;

Gansu Provincial Hospital of TCM;Gansu Provincial Hospital of TCM;Gansu Provincial Hospital of TCM;Gansu Provincial Hospital of TCM;Gansu Provincial Hospital of TCM

zhangly8848@126.com;zhangly8848@126.com;zhangly8848@126.com;zhangly8848@126.com;zhangly8848@126.com+86 18993031016;+86 18993031016;+86 18993031016;+86 18993031016;+86 18993031016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026