breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. women aged 18~65 and weigh 45-80kg; 2. need to undergo unilateral radical mastectomy plus implant placement; 3. American Society of anesthesiologists (ASA) grade I ~ II; 4. dysfunction of heart, lung, liver, kidney and blood coagulation; 5. no local anesthetic allergy history; 6. no drugs used to affect nerve function before operation.;Inclusion criteria: 1. women aged 18~65 and weigh 45-80kg; 2. need to undergo unilateral radical mastectomy plus implant placement; 3. American Society of anesthesiologists (ASA) grade I ~ II; 4. dysfunction of heart, lung, liver, kidney and blood coagulation; 5. no local anesthetic allergy history; 6. no drugs used to affect nerve function before operation.;Inclusion criteria: 1. women aged 18~65 and weigh 45-80kg; 2. need to undergo unilateral radical mastectomy plus implant placement; 3. American Society of anesthesiologists (ASA) grade I ~ II; 4. dysfunction of heart, lung, liver, kidney and blood coagulation; 5. no local anesthetic allergy history; 6. no drugs used to affect nerve function before operation.;Inclusion criteria: 1. women aged 18~65 and weigh 45-80kg; 2. need to undergo unilateral radical mastectomy plus implant placement; 3. American Society of anesthesiologists (ASA) grade I ~ II; 4. dysfunction of heart, lung, liver, kidney and blood coagulation; 5. no local anesthetic allergy history; 6. no drugs used to affect nerve function before operation.;Inclusion criteria: 1. women aged 18~65 and weigh 45-80kg; 2. need to undergo unilateral radical mastectomy plus implant placement; 3. American Society of anesthesiologists (ASA) grade I ~ II; 4. dysfunction of heart, lung, liver, kidney and blood coagulation; 5. no local anesthetic allergy history; 6. no drugs used to affect nerve function before operation.
Exclusion criteria
Exclusion criteria: 1. patients with inflammatory milk tumor; 2. patients with contraindications for radical mastectomy; 3. there are contraindications to nerve block, such as coagulation dysfunction, systemic or puncture site infection, local anesthetic allergy, nerve damage, etc.; 4. with severe heart, kidney, liver or respiratory diseases; 5. any cause that can not cooperate with the study, such as mental illness, language comprehension disorder, etc.;Exclusion criteria: 1. patients with inflammatory milk tumor; 2. patients with contraindications for radical mastectomy; 3. there are contraindications to nerve block, such as coagulation dysfunction, systemic or puncture site infection, local anesthetic allergy, nerve damage, etc.; 4. with severe heart, kidney, liver or respiratory diseases; 5. any cause that can not cooperate with the study, such as mental illness, language comprehension disorder, etc.;Exclusion criteria: 1. patients with inflammatory milk tumor; 2. patients with contraindications for radical mastectomy; 3. there are contraindications to nerve block, such as coagulation dysfunction, systemic or puncture site infection, local anesthetic allergy, nerve damage, etc.; 4. with severe heart, kidney, liver or respiratory diseases; 5. any cause that can not cooperate with the study, such as mental illness, language comprehension disorder, etc.;Exclusion criteria: 1. patients with inflammatory milk tumor; 2. patients with contraindications for radical mastectomy; 3. there are contraindications to nerve block, such as coagulation dysfunction, systemic or puncture site infection, local anesthetic allergy, nerve damage, etc.; 4. with severe heart, kidney, liver or respiratory diseases; 5. any cause that can not cooperate with the study, such as mental illness, language comprehension disorder, etc.;Exclusion criteria: 1. patients with inflammatory milk tumor; 2. patients with contraindications for radical mastectomy; 3. there are contraindications to nerve block, such as coagulation dysfunction, systemic or puncture site infection, local anesthetic allergy, nerve damage, etc.; 4. with severe heart, kidney, liver or respiratory diseases; 5. any cause that can not cooperate with the study, such as mental illness, language comprehension disorder, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score;Prince-Henry pain scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| pressing times of PCNA;The first time of additional analgesic;Dose of additional analgesic drug;Postoperative complications;degree of postoperative analgesia satisfaction; | — |
Countries
China
Contacts
First Affiliated Hospital of Chongqing Medical University;First Affiliated Hospital of Chongqing Medical University;First Affiliated Hospital of Chongqing Medical University;First Affiliated Hospital of Chongqing Medical University;First Affiliated Hospital of Chongqing Medical University