Goal-Directed Fluid Management
Conditions
Interventions
Control group:None
SVV group:Intraoperative fluid managment based on the goal of SVV<12%
IVC group:Postoperative fluid management based on IVC
Combine group:Fluid management based on intraoperative SVV<12% and postoperative IVC
Sponsors
Drum Tower Hospital, Medical College of Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Selective precise hepatectomy, aged 18-80 years, BIM 19-28kg/m2, ASA I-III, planned hepatic resection>3 segments, estimated operative time>4h and informed consent have been signed.;Inclusion criteria: Selective precise hepatectomy, aged 18-80 years, BIM 19-28kg/m2, ASA I-III, planned hepatic resection>3 segments, estimated operative time>4h and informed consent have been signed.;Inclusion criteria: Selective precise hepatectomy, aged 18-80 years, BIM 19-28kg/m2, ASA I-III, planned hepatic resection>3 segments, estimated operative time>4h and informed consent have been signed.;Inclusion criteria: Selective precise hepatectomy, aged 18-80 years, BIM 19-28kg/m2, ASA I-III, planned hepatic resection>3 segments, estimated operative time>4h and informed consent have been signed.;Inclusion criteria: Selective precise hepatectomy, aged 18-80 years, BIM 19-28kg/m2, ASA I-III, planned hepatic resection>3 segments, estimated operative time>4h and informed consent have been signed.
Exclusion criteria
Exclusion criteria: Cardiac function in NYHA II level and above, symptomatic arrhythmias compromised hemodynamics, severe anemia, obviously abnormal coagulant function, renal function in CKD 3 phase and above, liver function in Child-Pugh>9 scores, respiratory insufficiency, or central nervous system disorders.;Exclusion criteria: Cardiac function in NYHA II level and above, symptomatic arrhythmias compromised hemodynamics, severe anemia, obviously abnormal coagulant function, renal function in CKD 3 phase and above, liver function in Child-Pugh>9 scores, respiratory insufficiency, or central nervous system disorders.;Exclusion criteria: Cardiac function in NYHA II level and above, symptomatic arrhythmias compromised hemodynamics, severe anemia, obviously abnormal coagulant function, renal function in CKD 3 phase and above, liver function in Child-Pugh>9 scores, respiratory insufficiency, or central nervous system disorders.;Exclusion criteria: Cardiac function in NYHA II level and above, symptomatic arrhythmias compromised hemodynamics, severe anemia, obviously abnormal coagulant function, renal function in CKD 3 phase and above, liver function in Child-Pugh>9 scores, respiratory insufficiency, or central nervous system disorders.;Exclusion criteria: Cardiac function in NYHA II level and above, symptomatic arrhythmias compromised hemodynamics, severe anemia, obviously abnormal coagulant function, renal function in CKD 3 phase and above, liver function in Child-Pugh>9 scores, respiratory insufficiency, or central nervous system disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactic acid;Volume of liquid loss;Volume of liquid intake;Albumin;C-reactive protein;Total bilirubin;Direct bilirubin;Creatinine;Blood ureanitrogen;Time for dieting;Postoperative nausea and vomiting;Time for anal exhaust;days of hospital stay;Adverse events;30-day mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters;Temperature; | — |
Countries
China
Contacts
Public ContactBingbing Li;Bingbing Li;Bingbing Li;Bingbing Li;Bingbing Li ;;;;
Drum Tower Hospital, Medical College of Nanjing University;Drum Tower Hospital, Medical College of Nanjing University;Drum Tower Hospital, Medical College of Nanjing University;Drum Tower Hospital, Medical College of Nanjing University;Drum Tower Hospital, Medical College of Nanjing University
Outcome results
None listed