Meibomian Gland Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Compliance with MGD diagnostic criteria; 2. Aged 18 years and more; 3. To be willing and able to cooperate with study requirements; Agreed to use a reliable form of contraception if of childbearing potential
Exclusion criteria
Exclusion criteria: Had active ocular diseases, excluding glaucoma, or infections other than blepharitis;Had ocular surgery within the past 3 months; Had active ocular allergies;Had autoimmune disease requiring systemic treatment; Was unwilling or unable to discontinue the following medications during the study or during a 30-day washout period before the start of the study: systemic or ocular antibiotics, systemic or ocular steroids, anticholinergics,systemic or ocular antihistamines, ocular nonsteroidal antiinflammatory preparations, ocular vasoconstrictors, and investigational drugs other than the study drug; pregnant or nursing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tear break-up time, BUT;international ocular surface disease index(OSDI);the quality of expressed meibum;meibum expressibility; | — |
Secondary
| Measure | Time frame |
|---|---|
| corneal fluorescein staining(CFS);schirmer scores with no anaesthetic(schirmer I test,SIT);ocular symptom scores; | — |
Countries
China
Contacts
Longhua Hospital Shanghai University of TCM