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Establishment and Clinical Application study of Individualized Protective Ventilation Strategy in Elderly Patients during General Anesthesia

Establishment and Clinical Application study of Individualized Protective Ventilation Strategy in Elderly Patients during General Anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17012902
Enrollment
Unknown
Registered
2017-10-08
Start date
2016-01-01
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung injury

Interventions

Experimental group:Individualized lung protective ventilation strategy
Control group:Standardized lung protective ventilation

Sponsors

Sir Run Run Shaw Hospital,School of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: Aged =65 years; orthopedic surgery, including artificial joint replacement surgery and fractures surgery around hip joint; surgery time> 1 hours; body mass index <35 kg/m2.

Exclusion criteria

Exclusion criteria: Combined with ALI / ARDS; combined heart failure or suspected heart failure; received mechanical ventilation (including CPAP) treatment 15 days before surgery; combined pneumothorax or lung bullae; combined with craniotomy; moderate to severe liver and kidney dysfunction; combined with COPD requiring oxygen therapy or CPAP; access to ICU after surgery; participate in other clinical intervention trials.

Design outcomes

Primary

MeasureTime frame
Pulmonary complications within 7 days after surgery;—

Secondary

MeasureTime frame
sRAGE;IL-6;IL-10;TNF-a;—

Countries

China

Contacts

Public ContactJunran Xie

Sir Run Run Shaw Hospital,School of Medicine, Zhejiang University

xie_junran@163.com+86 13858126216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026