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Clinical effect of high flow nasal cannula oxygen therapy on sequential treatment of invasive ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease

Application of high flow nasal cannula oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17012720
Enrollment
Unknown
Registered
2017-09-19
Start date
2017-10-01
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Oxygen therapy group:nasal catheter oxygen
NIV group:Non-invasive ventilator sequential treatment
HFNC group :high flow nasal cannula oxygen sequential treatment

Sponsors

Northern Jiangsu Province Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The acute exacerbation of COPD patients complicated with respiratory failure treated with tracheal intubation, Continuous admitted in department of intensive care unit, the of Northern Jiangsu Province Hospital from September 2017 to December 2018. All cases are consistent with the 2016 chronic obstructive pulmonary disease diagnosis, treatment and prevention of global strategy guidelines Diagnostic criteria for COPD (the Global Initiative for Chronic Obstructive Lung Disease GOLD).

Exclusion criteria

Exclusion criteria: 1. Exclusion of other serious diseases, such as acute myocardial infarction, advanced tumors and so on; 2. Serious malnutrition; 3. Severe pulmonary hypertension (mean pulmonary artery pressure> 45 mmHg); 4. Patients with facial trauma or facial deformities.

Design outcomes

Primary

MeasureTime frame
28 days re-intubation rate;

Secondary

MeasureTime frame
mortality during 28 days;length of stay in ICU;length of stay in hospital;

Countries

China

Contacts

Public ContactYu Jiangquan

Northern Jiangsu Province Hospital

15651057659@163.com+86 15651057659

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026