Autism spectrum disorder
Conditions
Interventions
t-VNS group:NA
st-VNS group:NA
Sponsors
School of Public Health, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. DSM-5 will be used for the diagnosis of autism spectrum disorders: (1) The main problem is persistent deficits in social communication and social interaction; (2) Restricted, repetitive patterns of behavior, interests, or activities; (3) Symptoms must be present in the early developmental period; (4) Symptoms cause clinically significant impairment in social, occupational, or other important areas of current functioning; (5) These disturbances are not better explained by intellectual disability (intellectual developmental disorder) or global developmental delay. 2. Patients aged between 6-18 years; 3. uncorrected or corrected visual acuity; 4. right-handed; 5. Patients who can understand the content of scales and volunteer to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Mental disease except ASD (such as epilepsy, schizophrenia, mental retardation, etc.); 2. Severe nervous system disease; 3. history of brain injury; 4. other developmental behavior disorders (such as learning disabilities, attention deficit hyperactivity disorder, etc); 5. Severe somatic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines;magnetic resonance imaging (T1, DTI, rs-fMRI);Autism Treatment Evaluation Checklist;Childhood Autism Rating Scale;Social Responsiveness Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Screen for Child Anxiety Related Emotional Disorders;Child Quality of Life;Neurotransmitters (GABA, NE, 5-HT);Empathizing/Systemizing quotient, child version;The Children's Sleep Habits Questionnaire;Wechsler Intelligence Scale for Children-IV;Psychoeducational Profile-Third Edition;Conners Parent Symptom Questionnaire;behavior teat; | — |
Countries
China
Contacts
Public ContactYu Jin
School of Public Health, Sun Yat-sen University
Outcome results
None listed