Major Depressive Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) outpatients, aged 16~60 years (including 16 years and 60 years), with unlimited sex; 2) consistent with the American psychiatric diagnostic and Statistical Manual, version IV (DSM-IV) diagnostic criteria for major depressive disorder (confirmed by the MINI questionnaire), with first or recurrent symptoms, with no psychotic symptoms; 3) by visual analogue scale, the patient believes that his present illness (depression) has recovered 50% or more compared with the onset of this attack; 4) according to the doctor's judgment, patients is the use of antidepressant monotherapy. The category of antidepressants includes: Tricyclic and tricyclic antidepressants; Class SSRI antidepressants; Class SNRI antidepressants; Class NaSSA antidepressants; The NDRI class of antidepressants (such as bupropion etc.); Class SARI antidepressants (such as trazodone, trazodone, etc.); Alpha adrenergic receptor antagonists 2- and 5-HT1, 5-HT2 receptor antagonists (such as mianserin, etc.); Class NARI antidepressants (such as Rui, Posey, Ting, etc.); Other classes: Ago Mela Dean. 5) after this depression attack, the patient has used the antidepressant treatment for 8 weeks (including) -12 weeks (inclusive), during the cumulative interruption of treatment, the number of days not more than 2 weeks; 6) the total score of QIDS-SR16 was >5; 7) this patient except the medicine treatment, has not passed other treatment method treatment. Other therapies include: Traditional Chinese medicine, MECT, transcranial magnetic stimulation, biofeedback therapy, phototherapy, acupuncture and other physical therapy, and systematic psychotherapy; 8) above the elementary school education level, can understand the meter content, can skilled use the computer; 9) informed consent of the patient.
Exclusion criteria
Exclusion criteria: 1) clear history of mania or hypomania; 2) previous diagnosis of bipolar disorder, schizophrenia, schizophrenia, and other psychiatric disorders associated with mental disorders; 3) previously have Jiuyao dependent and patients with a history of acute poisoning; 4) female patients during pregnancy or lactation; 5) currently has a serious risk Dutch act, HAMD-17 Dutch act item score 3; 6) there are serious somatic disease researchers who do not consider it suitable for inclusion in this study; 7) make clear that do not want to participate in psychotherapy, or that psychological treatment invalid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QIDS-SR16; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMD-17;YMRS;ATQ;FISER/GRSEB;SDS;FBS;Q-LES-Q-SF; | — |
Countries
China
Contacts
The National Clinical Research Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.