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Single-center, Prospective Control random Trail on the impact of pre-oral slight liquid diet on stress and metabolic response in patients after duodenopancreatectomy

Single-center, Prospective Control random Trail on the impact of pre-oral slight liquid diet on stress and metabolic response in patients after duodenopancreatectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17012375
Enrollment
Unknown
Registered
2017-08-15
Start date
2017-09-11
Completion date
Unknown
Last updated
2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

experimental group:slight liquid diet
control group:10%Glucose 300ml
routine group:Fasting and water prohibition

Sponsors

Department of HBP Surgery, Changhai Hospital, Second Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged at least 18 years; 2. CT or MRI scans prompt tumor is aronud the head and the ampullar region of pancreas.No metastasis. Underwent pancreatoduodenectomy; 3. sign informed consent.

Exclusion criteria

Exclusion criteria: Preoperative fever, white blood cell proliferation and preoperative infection accompanied by systemic inflammatory diseases; Accompanied by nausea and vomiting, gastroesophageal reflux, gastric emptying, pyloric obstruction, etc.; Obesity (BMI>30) or severe malnutrition (BMI<15); Combined with severe brain, heart, lung, liver and kidney diseases, and hematological diseases; Anemia or received blood transfusions and nutritional support within 2 weeks before surgery; Bleeding in aged 1500ml; intraoperative blood transfusion; Diabetes mellitus, impaired glucose tolerance, and other metabolic diseases; Abandon experiment.

Design outcomes

Primary

MeasureTime frame
blood glucose;Insulin concentration;Insulin resistance index;CD4/CD8;superoxidase dismutase;MDA;CAT;

Secondary

MeasureTime frame
Albumin;transferrin;prealbumin;creatinine;urea nitrogen;CRP;PCT;IL-6;IL-8;TNF-a;CD4;CD8;

Countries

China

Contacts

Public ContactJin Gang

Department of HBP Surgery, Changhai Hospital, Second Military Medical University

jingang@sohu.com+86 13601635681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026