nasopharyngeal carcinoma
Conditions
Interventions
treatment:Safflower yellow pigment administration+routine nursing
Control group:Routine nursing
Sponsors
Jiangsu Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. newly diagnosed nasopharyngeal carcinoma diagnosed by pathology, clinical stage II to IVa (2010AJCC 7th); 2. Aged from 18 to 70 years male and female; 3. no head and neck surgery history, no chemotherapy history; 4. ECOG score 0-2 points; 5. no history of toothless disease; 6. the laboratory examination before chemotherapy and radiotherapy meets the following conditions: (1) liver function: total bilirubin = 1.5 times the upper limit of normal; aspartate aminotransferase and alanine aminotransferase = 2.5 times the upper limit of normal; alkaline phosphatase = 1.5 times the upper limit of normal; (2) renal function: creatinine clearance rate = 80ml / min; (3) blood function: absolute neutrophil count = 2×10^9/L, platelet count = 100×10^9/L, hemoglobin = 9g/dL; (4) blood glucose levels: good glycemic control, fasting blood glucose 3.9-7.2mmol/L, 2 hours after the meal blood glucose = 1.0mmol/L, glycosylated hemoglobin <7%. 7. no distant evidence of the metastasis; 8. no serious heart, liver, kidney dysfunction and radiotherapy and chemotherapy taboo; 9. Enhanced CT and MRI scans of the nasopharynx and neck before treatment, and / or PET / CT scan.
Exclusion criteria
Exclusion criteria: 1. Previously had anti-tumor therapy, including radiotherapy, chemotherapy and surgery; 2. distant metastases were found before treatment; 3. has oral mucositis or oral mucositis occurred repeatedly (1 times / month or more) before chemotherapy or radiotherapy; 4. with periapical inflammation; 5. pregnant or lactating women; 6. have severe heart, liver, lung, kidney dysfunction or poor blood sugar control, can not tolerate chemotherapy and chemotherapy; 7. Patients with mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral mucositis; | — |
Countries
China
Contacts
Public ContactLijun Wang
Jiangsu Cancer Hospital
Outcome results
None listed