arthritis
Conditions
Interventions
THA Experimental group:Intraoperative injection of analgesic drugs
TKA Experimental group:Intraoperative injection of analgesic drugs
THA Control group:Equal amount of normal saline
TKA Control group:Equal amount of normal saline
Sponsors
Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Chinese adult subjects, aged =18 years old male and female; 2. Target joint to be subjected to total hip arthroplasty, artificial total knee arthroplasty, a recent X-ray examination as a diagnostic basis; 3. Other pain relief treatments (drugs, acupuncture and other physical therapy) that have not been treated with roxecoxibraside; 4. Subjects can understand and sign informed consent that has been approved by the Independent Ethics Committee. Note: Informed consent may also be provided by the legally authorized representative of the subject; 5. After the hospital can still go to hospital for hospital visits.
Exclusion criteria
Exclusion criteria: 1. Subjects> 1 joint replacement (bilateral hip, knee replacement; ipsilateral hip, knee replacement, etc.); 2. With asthma, urticaria or the use of aspirin or other non-steroidal anti-inflammatory drugs after a history of allergic reactions; 3. Clinically significant lower limb venous or lymphatic reflux disorder; 4. Pregnant or lactating women; 5. Symptoms of multimodal analgesic drugs; 6. Diabetes is poorly controlled; 7. There are previous digestive system ulcers, bleeding; 8. Other special circumstances and refusal to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric Rating Scale scores;WOMAC score;Satisfaction score; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactChen Zhang
Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed