Overactive Bladder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: no menopause; Written informed consent has been obtained; Patient is willing and able to complete the 3-days micturition diary correctly; Symptoms of OAB (including urinary frequency, urgency with or without urge incontinence); the mean frequency of micturition=8 times per day, the frequency of nocturia=2 times per day, voiding volume<200ml each time; OABSS between 6 to 11, Urgency Score=2; unaltered sexual patner.
Exclusion criteria
Exclusion criteria: with severe cardiac diseases and arrhythmia; with severe hepatic and renal diseases, in which case aspartate aminotransferase, alanine aminotransferase and creatinine are 1.5 times greater than the upper limit of normal reference range; with contraindication of anticholinergic therapy, such as urinary retention, gastric retention, uncontrolled angle-closure glaucoma and allergy to Wenglitong capsules; acute urinary tract infection with symptoms during screening period; hematuria with unknown cause, cancer, interstitial cystitis, neurogenic bladder, bladder outlet obstruction, urethral catheterization, brain trauma, thyroid diseases, diabetes mellitus and other diseases which researchers recognized as unsuitable to be included in this trial; pregnancy, lactation or prepared to pregnancyrecently gave birth (i.e., within 6 months preceding the referral), had previous prolapse or incontinence surgery, or not beginning sexual activities (due to ethics problems) were excluded from this studysignificant stress incontinence or mixed stress / urge incontinence where stress is the predominant factor as determined by the investigator;PVR>50ml
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OABSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| FSFI;Electrical detection value of pelvic floor;spousal sexual function scores ; | — |
Countries
China
Contacts
The Fifth People's Hospital of Shanghai, Fudan University, China