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Effect of remote ischemic preconditioning on acute kidney injury after percutaneous coronary intervention---a randomized controlled trial

Effect of remote ischemic preconditioning on acute kidney injury after percutaneous coronary intervention---a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17011901
Enrollment
Unknown
Registered
2017-07-07
Start date
2018-12-01
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute kidney injury

Interventions

Control group: sham procedure with routine treatment

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Eligible patients were adults (=18 years of age) with a Mehran’s score for Prediction of Contrast-induced Nephropathy of 6 or higher for those receiving percutaneous coronary intervention or coronary angiography.

Exclusion criteria

Exclusion criteria: 1. Peripheral vascular disease or vascular surgery in the upper extremity; 2. The pulsation of the distal artery of the upper limb is not obvious; 3. Raynaud's syndrome; 4. Myocardial infarction within 7 days of surgery; 5. End stage renal disease(eGFR<15ml/min/1.73m2); 6. Presurgical AKI; 7. Pregnancy; 8. Renal transplantation; 9. In addition, allergy to iodine contrast agent or using contrast medium within one week for patients receiving percutaneous coronary intervention.

Design outcomes

Primary

MeasureTime frame
Serum creatinine;Blood Urea Nitrogen;Neutrophil gelatinase–associated lipocalin (NGAL);cTnT;Kidney injury molecule-1;Urinary tissue inhibitor of metalloproteinase 2 (TIMP-2);Insulin-like growth factor binding protein 7;

Countries

China

Contacts

Public ContactPing Jia

Zhongshan Hospital, Fudan University

jia.ping1@zs-hospital.sh.cn+86 137 6173 2850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026