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A predictive study of acupunctrue effect on depressive conbine insomnia based on 5-HTTLPR gene polymorphism, personality and brain network

A predictive study of acupunctrue effect on depressive conbine insomnia based on 5-HTTLPR gene polymorphism, personality and brain network

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17011839
Enrollment
Unknown
Registered
2017-07-03
Start date
2016-10-15
Completion date
Unknown
Last updated
2017-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive conbine insomnia

Interventions

acupuncture group:acupuncture and intradermal needling
placebo group:placebo needle

Sponsors

The Guangdong provincial hospital of Chinses medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. meet the criteria of diagnosed depressive disorder according to CCMD-3DSM-V; 2. insomnia is the major complaint with HAMD score between 20 and 35, PSQI more than 7; 3. participants should in conscious, without aphasia and comprehand the scales well; 4. right handedness; 5. aged between 18 and 65 years.

Exclusion criteria

Exclusion criteria: 1. cerebral trauma, secondery depressive insomnia related to organic mental disorders and non-addictive substances; 2. suicidal tendency or claustrophobia; 3. pregnant,serious cardiovascular, liver, kediney or hemopoietic system diseases; 4. can not comprehend the scales well or low compliance.

Design outcomes

Primary

MeasureTime frame
HAMD;PSQI;SDS;—

Secondary

MeasureTime frame
EPQ;5-HTTLPR gene polymorphism;rest state brain functional network;—

Countries

China

Contacts

Public ContactLuo Ding

The Guangdong provincial hospital of Chinses medicine

doctorluoding@163.com+86 18898607006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026