Protrusion of lumbar intervertebral disc
Conditions
Interventions
the corticosteroid group:ultrasound guided Injection of corticosteroid through intervertebral foramen
the PRP group:ultrasound guided Injection of PRP through intervertebral foramen
Sponsors
Sun Yat-sen Memorial Hospital,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) aged 20-60 years; (2) low back pain with unilateral lower limb radioactive pain, duration of more than 3months; (3) lumbar disc herniation were diagnosed by MRI or CT, and consistent with the clinical symptoms and signs; (4) no symptoms of nerve damage symptoms; (5) the patients have got conservative treatment, including physical therapy, the manipulation and non morphine treatment; (6) the degree of pain (VAS) is more than 5 and there are obvious nerve root irritation symptoms and clinical signs; (7) who had no history of spinal surgery.
Exclusion criteria
Exclusion criteria: (1) infection; (2) spinal tumors or tuberculosis; (3) severe diabetes; (4) a history of drug abuse or oral anticoagulation; (5) multi segmental lumbar disc herniation, spinal deformity or existing structure, spinal stenosis; (6) abnormal psychological, cognitive disorders; (7) not suitable for local injection; (8) had received prior treatment for injection in the past 3months, such as the injection of nerve root, sacral injection tube; (9) during pregnancy; (10) allergic to the drug used in the study; (11) clinical diagnosis of heart disease, liver and kidney dysfunction, blood system diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pressure pain thresholds;visual analogue scale;Oswestry disability index;SF-36; | — |
Secondary
| Measure | Time frame |
|---|---|
| F wave latency;the rate of F wave; | — |
Countries
China
Contacts
Public ContactChao Ma
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed