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A Clinical Control Study of Navigated fMRI-guided rTMS Personalized Precision Treatment and traditional Treatment of Post-stroke Depression

A Clinical Control Study of rTMS Personalized Precision Treatment of Post-stroke Depression Based on Mechanism of Emotional Circuit Imbalance

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17011659
Enrollment
Unknown
Registered
2017-06-14
Start date
2017-07-01
Completion date
Unknown
Last updated
2017-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke depression

Interventions

experimental group:rTMS precision treatment combination therapy of drugs
control group:Traditional rTMS treatment combination therapy of drugs

Sponsors

Zhujiang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients must meet the diagnostic criteria for major depressive episode (China Classification and diagnostic criteria for mental disorders third edition, CCMD-3) and whose Hamilton Depression Scale (HAMD) scores were more than 17 were collected; 2. Patients must be diagnosed by CT or MRI diagnosed as a single medium-sized lesion infarction (2-5cm); 3. Dextromanuality; Clear consciousness; 4. Aged 25-75 years old male and female; The duration of less than 24 months; 5. No previous history of depressionagreed to accept the treatment of this study, and signed the "informed consent of treatment."

Exclusion criteria

Exclusion criteria: 1. With severe dementia, aphasia, consciousness disorder, deafness, and other serious physical diseases that affect depressive mood; 2. A previous history of depression, a family history of mental illness; 3. Depression caused by psychoactive substances and non addictive substances; 4. With a history of brain surgery or brain implants, placement of pacemakers and hearing aids in the ear; 5. Pregnant and lactating women; 6. Those who are unwilling to accept the experiment or have difficulty in completing the experiment; 7. Not agree to participate in this study.

Design outcomes

Primary

MeasureTime frame
Treatment efficiency;

Secondary

MeasureTime frame
Excellent rate of treatment;NIHSS score;SAS score;ADL score;fMRI, DTI score;

Countries

China

Contacts

Public ContactWu Wen

Zhujiang Hospital, Southern Medical University

wuwen66@163.com+86 020-62783189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026