locally advanced gastric cancer
Conditions
Interventions
neoadjuvant chemotherapy combined surgery group:eoadjuvant chemotherapy combined surgery
surgery alone group:surgery alone
Sponsors
Jinling Hospital, Medical School of Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with locally advanced gastric cancer; 2. Aged 18 to 75 years; 3. ASA class I-III; 4. Participants can describe the symptom objectively and cooperate actively; 5. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients allergic to oxaliplatin, tegafur gimerac etc.; 2. Patients with ischemic heart disease, cerebrovascular disease and peripheral vascular disease, or cardiac function > II (NYHA); 3. Patients with complications (bleeding, perforation and obstruction) caused by gastric cancer; 4. Patients with severe liver and renal dysfunction (Child – Pugh = 10; Cr < 25 ml/min); 5. Patients who require simultaneous surgery for other diseases; 6. Patients who received upper abdominal surgery previously; 7. Pregnant or breast-feeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative length of stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative complications;time to first flatus;time to semi-liquid diet;nutritional status; | — |
Countries
China
Contacts
Public ContactZhi-Wei JIANG
Jinling Hospital, Medical School of Nanjing University
Outcome results
None listed