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Effect of R1/R2 resection on prognosis of patients with stage IV intrahepatic cholangiocarcinoma: A prospective, randomized, multicenter study

Effect of R1/R2 resection on prognosis of patients with stage IV intrahepatic cholangiocarcinoma: A prospective, randomized, multicenter study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17011404
Enrollment
Unknown
Registered
2017-05-15
Start date
2017-05-01
Completion date
Unknown
Last updated
2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intrahepatic cholangiocarcinoma

Interventions

operation group:R1/R2 resection
radiotherapy group:Stereotactic radiotherapy
chemotherapy:Fluorouracil and gemcitabine chemotherapy
control group:none

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with stage 4 TNM Confirmed by histology or cytology, or clinical diagnosis of ICC.

Exclusion criteria

Exclusion criteria: 1. Patients received any form of antineoplastic therapy before surgery: radiotherapy, chemotherapy, or biological therapy; 2. Patients with severe cardiovascular and cerebrovascular diseases which may have an impact on the expected life cycle; 3. Patients who have or are suffering from other malignancies, or who have been treated for cancer within 3 years, have the following conditions: cured cervical cancer, basal cell carcinoma of the skin and superficial bladder cancer (Ta,Tis,T1); 4. Patients with multiple metastasis of the body, and poor fluid quality, who are expected to survive for no more than 6 months of the patient; 5. Patients who did not complete the chemoradiotherapy regimen as planned.

Design outcomes

Primary

MeasureTime frame
overall survival;

Countries

China

Contacts

Public ContactZhang Guowei

Nanfang Hospital, Southern Medical University

guoweizhangy72@163.com+86 13600039982

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026