Diabetic foot
Conditions
Interventions
test group:Tibial transverse bone transport microcirculation reconstruction
Control group:Control of blood sugar, lipid, anticoagulation, anti-platelets, vasodilators and other traditional treatment
Sponsors
Department of Orthopedics, the Fifth Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. diagnosed diabetic foot ulcers Wagner stage 2-4 patients; 2. older than 18 years old, and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. recent diabetic ketoacidosis, hyperosmolar coma or severe chronic diabetes complications and other stress conditions such as acute heart, cerebrovascular accident; 2. peripheral arterial lesions can not be more than the middle of the artery; 3. creatinine is higher than the normal upper limit of 1.5 times or serum creatinine concentration =133 umol/L (male)/124umol/L (female), such as aspartate aminotransferase or alanine aminotransferase, Or creatinine clearance <60 mL/min; 4. severe lung infection, cardiopulmonary dysfunction control poor; 5. severe hypoproteinemia (albumin levels below 30 g/L); 6. hemoglobin less than 90 g/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Limb salvage rate;Pain VAS score;Skin temperature feeling;Vascular remodeling;Complications occur;Wagner stage improvement;Ankle brachial index;10 g nylon thread test; | — |
Countries
China
Contacts
Public ContactYongjian Sun
Department of Orthopedics, the Fifth Affiliated Hospital of Southern Medical University
Outcome results
None listed