Gustilo III type open fractures with bone defect
Conditions
Interventions
Group A:improved Masquelet technique treatment
Sponsors
Daping Hospital, the Third Military Medical University, Chongqing, China
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. In-patients aged from 18 to 65 years men and women; 2. Gustilo type III open fractures with bone defect at least 5cm; 3. subjects are Voluntary and sign the informed content, attending the research.
Exclusion criteria
Exclusion criteria: 1. in addition to the limbs open fracture merge in areas such as the head, chest, abdomen injury of multiple trauma; 2. pregnancy, or nursing mothers, or ready to pregnant women; 3. associated with other serious disease, including liver, kidney, cardiovascular disease; 4. NYHA class II ~ IV heart function failure or nearly 3 months of myocardial infarction, stroke and other cardiovascular events; 5. liver meritorious service is significantly abnormal, or any of the following history of liver disease: 2 times higher than normal amount of AST and ALT limit, liver cirrhosis, hepatic encephalopathy history, history of history of esophageal varices or portal vein shunt; 6. a history of renal damage evidence or the following kidney disease: serum creatinine 1.5 times higher than normal limit; The history of dialysis;History or nephrotic syndrome; 7. merge all sorts of acute infection, tumor and severe arrhythmia, mental system disorders, drug or alcohol addiction; 8. the bone cement, vancomycin allergies or have contraindications in past 3 months; 9. into the group or the group participated in other clinical trials; 10. you have any medical history, according to the researchers may interfere with the test result or increase the risk of patients; 11. difficult to complete the visitor, or the various factors influencing the compliance; 12. refused to sign the informed consent, do not agree to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| erythrocyte sedimentation rate ;leukocyte;Neutrophils;C-reactive protein; | — |
Countries
China
Contacts
Public ContactJun Fei
Daping Hospital, the Third Military Medical University, Chongqing, China
Outcome results
None listed