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Effect of Qingshen Granules on E-cadherin protein in chronic renal failure patients with Damp-heat Syndrome

Effect of Qingshen Granules on E-cadherin protein in chronic renal failure patients with Damp-heat Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17011056
Enrollment
Unknown
Registered
2017-04-04
Start date
2017-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic renal failure

Interventions

treatment group:Basic treatment of Western Medicine+Enema with TCM+Qingshen Granules
control group:Basic treatment of Western Medicine+Enema with TCM

Sponsors

the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 70 years old; 2. Accord with the diagnostic criteria of chronic kidney disease (CKD) from 3 to 5, without renal replacement therapy; 3. Accord with the diagnostic criteria of damp-heat syndrome of TCM; 4. The blood pressure is less than 140/90mmHg, potassium less than 5.5mmol/L, hemoglobin more than 80g/L, infection controled,state of illness is stable for more than 2 weeks; 5. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating patients; 2. A person who is unable to cooperate, such as a psychotic; 3. Combined with active malignant tumor, liver cirrhosis, decompensated or hematopoietic system and other serious primary diseases; 4. Patients with infectious diseases, acute urinary tract obstruction, surgical treatment; 5. Severe arrhythmia, severe heart failure, grade NYHA or above (New York Heart Association grade III, IV),or in the first 3 months of suffering from myocardial infarction or cerebrovascular events; 6. Patients diagnosed with diabetic nephropathy; 7. Corticosteroids, non steroidal anti-inflammatory drugs or immunosuppressive agents are being used; 8. Known to be allergic to certain drugs in the study; 9. Patients participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
eGFR;

Secondary

MeasureTime frame
serum creatinine;Urea nitrogen;Serum electrolyte;Parathyroid hormone;24 hour urine protein quantitation;TCM Syndrome;

Countries

China

Contacts

Public ContactYiping Wang

the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

wypwyp54@aliyun.com+86 13075580986

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026