burn trauma & chronic wound
Conditions
Interventions
cell sheet graft treatment:cell sheet graft treatment
sulfadiazine silver treatment: sulfadiazine silver and tuojiagao control treatment
Sponsors
Changhai Hospital of Second Military Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Full-thickness trauma, 1~30% TBSA, the single observable wound bed is no less than 10×10 cm2, and no more than 10% TBSA; 2. Male and female aged 1~60 years; 3. Outpatient and inpatient, within 5 days of injury; 4. Childbearing-age woman need practice contraception; 5. Informed consent form is fully understood and signed for patients.
Exclusion criteria
Exclusion criteria: 1. HIV1,HIV2,HBV,HCV,HTLV1 or syphilis positive; 2. diabetic, malignant tumor or chronic wasting disease patient; 3. severe heart, liver, kidney and blood system complication; 4. using recombination human epidermal growth factor patient; 5. immune disease or hormone therapy patient; 6. pregnant or nursing women or supposed to be pregnant during clinical trial; 7. Physical or psychical situation are not suitable for clinical trial; 8. severe part or full body infection that are hard to control; or having active tuberculosis history or being active tuberculosis patient; 9. under other drug or medical instrument clinical trial within 30 days. Positive findings on test for HIV1, HIV2, HBV, HCV, HTLV1, or Syphilis; Patients were excluded if they had actively infected foot ulcers, significant lower extremity ischaemia: foot pulses (dorsalis pedis, posterior tibialis) on the affected foot were impalpable, acute Charcots disease or if they were judged not to be sufficiently compliant with the recommendations concerning off-loading and the regularity of the TranCell dressin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the healing rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| the healing time;pain visual analog scales; | — |
Countries
China
Contacts
Public ContactShichu Xiao
Shanghai Changhai Hospital
Outcome results
None listed