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The influence of goal-directed fluid therapy on the early postoperative cognitive function after spinal canal stenosis surgery in elderly patients

The influence of goal-directed fluid therapy on the early postoperative cognitive function after spinal canal stenosis surgery in elderly patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17010679
Enrollment
Unknown
Registered
2017-02-19
Start date
2017-02-28
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal canal stenosis

Interventions

the GDFT Gtoup:treatment of goal-directed fluid therapy during surgery

Sponsors

The First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Elderly patients who older than 60 years; 2. Thoracic and lumbar vertebra canal stenosis selective surgery; 3. ASA status I-II; 4. BMI<30 kg/m2; 5. Hct=30% before surgery; 6. patients can effective communication with doctor.

Exclusion criteria

Exclusion criteria: 1. Chronic disease (COPD, hypertension,diabetes,coronary heart disease,etc); 2. participants with psychiatric diseases; 3. those undergoing treatments that would affect cognitive function (such as antidepressants, pain medications, sleep aids, benzodiazepines, etc.),addictions; 4. clear arrhythmia; 5. liver and kidney dysfunctions and other severe cardiopulmonary diseases.

Design outcomes

Primary

MeasureTime frame
hemodynamic indexes;cerebral regional oxygen saturation, rSO2;tissue perfusion indexes;MoCA test;IL-6;S100ß;

Countries

China

Contacts

Public ContactZeng Kai

The First Affiliated Hospital of Fujian Medical University

zengkai6822@163.com+86 13055291712

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026