non-premonitory migraine
Conditions
Interventions
two:transcutaneous stimulation of the auricular branch of the vagal nerve (auricular t-VNS)
Control:sham-tVNS
Sponsors
Guangdong Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. 2004 years of IHS diagnosis criteria for migraine aura; 2. aged 18-45 years old, right-handed; 3. duration more than 6 months, and 2 times less than the number of episodes per month less than or equal to 6 times; 4. March to nearly not taking psychotropic or vasoactive drugs, near January did not receive electroacupuncture or he preventive treatment.
Exclusion criteria
Exclusion criteria: 1. special types of diseases caused by headache or migraine; 2. Onset within 48 hours or during the study; 3. pregnancy or lactation; 4. with other serious diseases or other diseases caused by chronic pain; 5. serious skull asymmetry or intracranial lesions; 6. SAS or SDS standard more than 50 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of days of moderate / severe migraine attack /28 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Migraine specific quality of life questionnaire (MSQ);Regional Homogeneity (ReHo);Brain Functional Connectivity Analysis;Brain iron metabolism;Fanctional Network Analysis; | — |
Countries
China
Contacts
Public ContactChen Jun
Guangdong Provincial Hospital of TCM
Outcome results
None listed