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A comparative study of Rivaroxaban, low-molecular-weight heparin, and sequential medication regimens for the prevention of venous thrombosis after internal fixation of hip fracture

A comparative study of Rivaroxaban, low-molecular-weight heparin, and sequential medication regimens for the prevention of venous thrombosis after internal fixation of hip fracture

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17010495
Enrollment
Unknown
Registered
2017-01-22
Start date
2011-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hip fracture

Interventions

Rivaroxaban group:oral Rivaroxaban
low-molecular-weight heparin group:hypodermic injection low-molecular-weight heparin
sequential therapy group:low-molecular-weight heparin with sequential Rivaroxaban

Sponsors

The Second Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: fractures were caused by fall-induced damage, the patients were admitted to the hospital within 24h after injury,the patients were diagnosed by X-ray or CT, and all patients received internal fixation.

Exclusion criteria

Exclusion criteria: lower extremity DVT was confirmed by preoperative imaging, the patients had a history of thromboembolic disease and were undergoing anticoagulant therapy, the patients with hemorrhagic diseases or major bleeding history (such as intracranial hemorrhage or gastrointestinal bleeding that required blood transfusion), the patients who were accompanied by severe liver diseases, the patients with coagulation disorders or contraindications to anticoagulation, and the patients who were contraindicated to Rivaroxabanor low-molecular-weight heparin.

Design outcomes

Primary

MeasureTime frame
the incidence of postoperative VTE;

Secondary

MeasureTime frame
compliance;treatment costs;bleeding;wound complications;

Countries

China

Contacts

Public ContactTang Yilun

the Second Affiliated Hospital of Xi'an Jiaotong University

a_lun1111@163.com+86 13201510034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 9, 2026