septic shock
Conditions
Interventions
experimental group:basic treatment of septic shock and tcm treatment based on syndrome differentiation
Sponsors
GuangDong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) diagnostic criteria for septic shock; (2) syndrome of heat toxin and blood stasis and yang deficiency and blood stasis syndrome; (3) older than 18 year old; (4) informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with acute myocardial infarction; (2) Patients with severe sepsis of other syndromes, such as excess syndrome and yin deficiency syndrome etc.; (3) Patients with severe bleeding tendency or active bleeding; (4) Allergic or allergic skin test in patients with the effect of drugs; (5) Patients who could not cooperate with the study and who had died within ICU24 hours, as well as the expected short period of death ( 300, or need emergency CRRT; (7) Liver dysfunction, total bilirubin >100umol/L; (8) Pregnant and lactating women; (9) Mental or legal disability; (10) Clinical trials of other drugs in the first 3 months of the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean arterial pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| PiCCO hemodynamic parameters CO, CI, SV, SVRI, EVLWI, CVP;Tissue perfusion index ScvO2, Pa-vCO2, Lac;Serum myocardial injury markers BNP, cTnI;Inflammation index;Safety index;28 day mortality;SOFA score; | — |
Countries
China
Contacts
Public ContactHe Jianzhuo
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed