general anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Informed consent; 2. Aged >=18 years old female; 3. ASA I~II; 4. BMI between 18kg/m2 to 30kg/m2; 5. Elective non-cardiac surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. The central nervous system disease; 2. Using any drugs known to affect EEG preoperative such as antipsychotics, sedatives, anti-epileptic drugs, central nervous system stimulants, including alcohol; 3. Allergy to any ingredient of propofol and remifentanil; 4. The emergency surgery; 5. Implanted electronic devices, for example, a patient fitted with a pacemaker, etc; 6. Pregnant women and lactating women; 7. Serious cardiovascular, respiratory, kidney or muscle disease history; 8. Abnormal liver function, liver function higher than 1.5 times the upper limit of normal; 9. Renal dysfunction, creatinine clearance 133µmol / L; 10. Inappropriately controlled or difficult to controlled hypertension: non-invasive systolic blood pressure (SBP) >=160mmHg or non-invasive diastolic blood pressure (DBP) >=100mmHg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| global score;the percentage of satisfactory anesthesia time;propofol consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| recovery time;perioperative adverse events;somatic events;blood loss;intraoperative recall; | — |
Countries
China
Contacts
The Fourth Hospital of Hebei Medical University