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Clinical Research and Evaluation of a closed-loop target controlled infusion system for infusion of propofol in patients receiving total intravenous anesthesia

Clinical Research and Evaluation of a closed-loop target controlled infusion system for infusion of propofol in patients receiving total intravenous anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17010399
Enrollment
Unknown
Registered
2017-01-11
Start date
2017-01-01
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia

Interventions

Sponsors

The Fourth Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Informed consent; 2. Aged >=18 years old female; 3. ASA I~II; 4. BMI between 18kg/m2 to 30kg/m2; 5. Elective non-cardiac surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. The central nervous system disease; 2. Using any drugs known to affect EEG preoperative such as antipsychotics, sedatives, anti-epileptic drugs, central nervous system stimulants, including alcohol; 3. Allergy to any ingredient of propofol and remifentanil; 4. The emergency surgery; 5. Implanted electronic devices, for example, a patient fitted with a pacemaker, etc; 6. Pregnant women and lactating women; 7. Serious cardiovascular, respiratory, kidney or muscle disease history; 8. Abnormal liver function, liver function higher than 1.5 times the upper limit of normal; 9. Renal dysfunction, creatinine clearance 133µmol / L; 10. Inappropriately controlled or difficult to controlled hypertension: non-invasive systolic blood pressure (SBP) >=160mmHg or non-invasive diastolic blood pressure (DBP) >=100mmHg.

Design outcomes

Primary

MeasureTime frame
global score;the percentage of satisfactory anesthesia time;propofol consumption;

Secondary

MeasureTime frame
recovery time;perioperative adverse events;somatic events;blood loss;intraoperative recall;

Countries

China

Contacts

Public ContactHongmeng Xu

The Fourth Hospital of Hebei Medical University

xuhongmeng66@aliyun.com+86 13603110056

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026